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Grey’s Anatomy • SEASON 2 EPISODE 11

Owner of a Lonely Heart

Grey’s AnatomySeason 2Episode 11Dec 4, 200543 min

Cristina Yang has little sympathy for Constance Ferguson (special guest star Rosanna Arquette), a prison inmate who jeopardizes her health just to get out of solitary confinement. Meanwhile the interns all keep careful watch on the family of premature quintuplets with a variety of serious health challenges, Izzie's anger at Alex reaches boiling point, and Dr. Addison Shepherd decides to teach Izzie a very painful lesson.

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